Usually, yes
CC0 is intended to permit both commercial and noncommercial reuse. That can include advertising, products, client work, publishing, and software.
Check the asset, not just the page
Confirm that the CC0 statement applies to the exact file and that the source is credible. Save a copy of the item page, creator details, and rights statement with your project records.
Rights outside copyright
Commercial use can increase trademark, privacy, publicity, and consumer-protection risk. A recognizable person, logo, branded product, private location, or sensitive context may require additional review or permission.
Put it into practice
Check your planned use
Select the exact license and use case to open a permanent result page.
Open compatibility checker